RESEARCH IN THE FIELD OF DEVELOPMENT OF TECHNOLOGY AND COMPOSITION OF TABLETS OF RUBIAE TINCTORUM EXTRACT

Abstract

In this study, a scientifically grounded composition and preparation technology for a tablet dosage form with effective therapeutic effects against kidney stone disease were developed based on the natural resources of Uzbekistan. The physicochemical and technological properties of the active pharmaceutical substance were studied, and 70% ethyl alcohol was selected as the composition of the excipients and the binder. The technological parameters of the tablet mass prepared using the wet granulation method have significantly improved. The pressing process was carried out on modern equipment, and the finished tablet fully met pharmacopoeia requirements. The results obtained serve as a basis for creating high-quality and safe import-substituting drugs in the local pharmaceutical industry.